What are the

Collagen
Peptides?

Collagen is the most abundant protein in the human body. It is an important component for the health of connective tissues such as skin, bones, muscles, tendons and cartilage.

Collagen molecules are composed of three polypeptide chains in a triple helix formation, making them stable and resilient structures that provide elasticity and support to various organs and tissues.

However, time and an unhealthy lifestyle causes the decrease of this protein in the body. With this, the signs of aging appear: joint pain, bone fragility, loss of muscle strength and function, wrinkles, and rough skin.

Collagen is

the Protein

of life!

It is present throughout the whole body

It is essential for the health of joints, skin, bones, muscles and tendons.

It represents about 30% of the total body protein

It is essential for the metabolism and activity of connective tissue cells.

Why consume

Collagen
Peptides?

It is very important that collagen-producing cells are stimulated to increase their production. Oral supplementation with collagen peptides prevents and attenuates the signs of aging by stimulating cells to naturally produce collagen and partially restoring the extracellular matrix.

Decades of data from the literature have shown that ingesting collagen peptides promotes improvements such as:

• Decreases wrinkle formation
• Increases skin elasticity
• Increases hydration
• Increases content, density, and synthesis of collagen
• Increases bone strength, density, and mass
• Improvement of joint stiffness/mobility, and functionality
• Joint pain reduction

Contact

Learn more about

Genu-in Life

Genu-in Life is a natural, bioactive and high purity product with:

• Protein rate greater than 97% (based on dry weight);

• Contains 18 amino acids, which are the main components of proteins. Glycine, proline and hydroxyproline make up about 50% of Genu-in Life's total amino acid content (10-20 times higher compared to other proteins)

Genu-in Life collagen peptides are optimized for high bioavailability and bioactivity. It means that they quickly reach the parts of the body where they are most needed, especially the most damaged connective tissues, as they are more susceptible to external stimulation. (Zague, et al. 2018*).

*Zague V et al. Collagen peptides modulate the metabolism of extracellular matrix by human dermal fibroblasts derived from sun-protected and sun-exposed body sites. Cell Biol Int. 2018 Jan;42(1):95-104.

Different forms of application

Powder

Sachets

Dairy products

Protein bars

among others!

360° ACTION

GUARANTEE
OF ORIGIN

SUPPORTED
BY SCIENCE

NEUTRAL ODOR AND TASTE

GLUTEN &
LACTOSE-FREE

GMO-FREE

What does the science
say about Collagen

Peptide
Absorption?

According to Richelle et al. (2006)*, bioavailability is defined as the relative amount of a bioactive compound that crosses the intestinal barrier, reaches the bloodstream and is available for metabolic processing or storage in the body.

A study carried out by Ohara et al. (2017)** demonstrated the rapid appearance of collagen peptides in the bloodstream after oral ingestion. Furthermore, the authors verified a maximum concentration of the protein in the blood just two hours after oral ingestion.
‍
*Richelle M, et al. Skin bioavailability of dietary vitamin E, carotenoids, polyphenols, vitamin C, zinc and selenium. Br J Nutr. 2006 Aug;96(2):227-38
**Ohara H et al. Comparison of quantity and structures of hydroxyproline-containing peptides in human blood after oral ingestion of gelatin hydrolysates from different sources. J Agric Food Chem 2007;55:1532–1535.

Benefits

Check out some of the benefits of taking
Genu-in Life Collagen Peptides

Skin health

Research regarding the effects of collagen peptides on skin health have produced very promising results indicating improved hydration and reduced wrinkles as benefits.

Evans et al. (2021)** evaluated 85 women aged between 45 and 60 years in a twelve-week randomized clinical trial. When administering 10g of collagen peptides, the researchers observed an improvement in the elasticity, hydration, brightness and firmness of the skin, in addition to a decrease in the presence of wrinkles.

After evaluating eleven randomized clinical trials, Choi et al. (2019)*** concluded that consumption of collagen peptides improves skin elasticity, hydration, collagen density, skin healing, and protects the skin against aging.

*Asserin J et al. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J Cosmet Dermatol. 2015 Dec;14(4):291-301.
**Evans M. et al. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J. Cosmet. Dermatol. 20 (3) (2021), pp. 825-834.
***Choi FD. et al. Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. J Drugs Dermatol. 2019 Jan 1;18(1):9-16.

A randomized clinical trial by Asserin et al. (2015)* found that participants who consumed collagen peptides showed a significant increase in collagen density in the dermis after four weeks of supplementation.

*Asserin J et al. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J Cosmet Dermatol. 2015 Dec;14(4):291-301.

Joint health

Collagen is a key component of cartilage, the connective tissue that sits between bones and provides smoother joint movement. The degradation of this tissue is a hallmark of several joint diseases that cause discomfort, stiffness, and reduced mobility. Most clinical studies with collagen peptide supplementation show significant reduction in pain and increased mobility compared to groups that consumed placebo.

Kumar et al. (2015)** investigated the effects of collagen peptide supplementation in subjects with knee osteoarthritis through a randomized, double-blind, placebo-controlled study. The researchers found that participants who received the protein had significant improvements in knee joint pain, mobility, and quality of life compared to the placebo group.

*Clark KL, et al. 24-week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Curr Med Res Opin 2008;24:1485–1496.
**Kumar S., et al. A double-blind, placebo-controlled, randomised, clinical study on the effectiveness of collagen peptide on osteoarthritis, J. Sci. Food Agric. 95 (4) (2015) 702–707.

Clark et al. (2008)* studied the effect of hydrolyzed collagen on joint pain related to physical activity in athletes. The results indicated that collagen peptides could possibly be used to reduce the risk of joint deterioration in a high-risk group.

*Clark KL, et al. 24-week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Curr Med Res Opin 2008;24:1485–1496.

Bone health

Collagen plays a fundamental role in maintaining the structural integrity of bones. It forms an organic matrix on which minerals such as calcium are deposited, providing a unique combination of flexibility and strength.

Kim et al (2013)* found, in an experimental study, that protein supplementation increases bone mineral density. Also, Moskowitz (2000)** concluded that collagen peptides can help maintain bone health, especially in conditions such as osteoarthritis and osteoporosis.

A study by König et al. (2018)*** investigated the effects of collagen supplementation on bone mineral density in postmenopausal women with osteopenia (a condition characterized by gradual loss of bone mass). The results indicated that participants who took collagen peptides had an increase in bone mineral density in the lumbar spine compared to the control group. This suggests that the protein may also play a role in mitigating bone loss.
‍
*Kim HK et al. Osteogenic activity of collagen peptide via ERK/MAPK pathway mediated boosting of collagen synthesis and its therapeutic efficacy in osteoporotic bone by back-scattered electron imaging and microarchitecture analysis. Molecules. 2013 Dec 12;18(12):15474-89.
**Moskowitz RW. Role of collagen hydrolysate in bone and joint disease. Semin Arthritis Rheum. 2000 Oct;30(2):87-99.
***König D et al. Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study. Nutrients. 2018 Jan 16;10(1):97.

Osteoporosis (a condition characterized by decreased bone density) is a constant concern, especially among the elderly population, but collagen peptides have drawn attention as an intervention with great potential in this context.

Muscle health

Crucial not just for connective tissues, collagen is also critical for muscle composition. Its fibers form a part of the extracellular matrix of these tissues, providing structural support and contributing to their functions.

Another study by Zdzieblik et al. (2015)** evaluated the influence of protein supplementation with collagen peptides on muscle mass and function after resistance training in men with sarcopenia (a syndrome characterized by progressive loss of muscle mass). They found that, compared to the placebo group, collagen peptide supplementation combined with resistance training further improved body composition, increasing lean mass and muscle strength, and decreasing fat mass.

A study by Jendricke et al (2019)*** investigated the effects of physical exercise combined with supplementation of specific collagen peptides on body composition and muscle strength in premenopausal women. The researchers concluded that there was an increase in lean mass and muscle strength compared to the placebo group. In addition, there was a significantly greater loss of fat and a more visible increase in leg strength.
‍
*Zdzieblik et al. The Influence of Specific Bioactive Collagen Peptides on Body Composition and Muscle Strength in Middle-Aged, Untrained Men: A Randomized Controlled Trial. Int J Environ Res Public Health 2021 Apr 30;18(9):4837
**Zdzieblik D. et al. Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial, Br. J. Nutr. 114 (8) (2015) 1237–1245.
***Jendricke P. et al. Specific collagen peptides in combination with resistance training improve body composition and regional muscle strength in premenopausal women: a randomized controlled trial,Nutrients. 2019 Apr 20;11(4):892.

A study by Zdzieblik et al. (2021)* explored the effectiveness of the protein (combined with resistance training) on body composition and muscle strength in non-athlete middle-aged men. In conclusion, supplementation with collagen peptides was associated with a significant increase in lean mass and a decrease in fat.

*Zdzieblik et al. The Influence of Specific Bioactive Collagen Peptides on Body Composition and Muscle Strength in Middle-Aged, Untrained Men: A Randomized Controlled Trial. Int J Environ Res Public Health 2021 Apr 30;18(9):4837.

Contact Us!

Collagen with control since

the origin

Genu-in only has products of known origin, manufactured from raw material generated by JBS. With this, we guarantee purity, consistency, and traceability through the Control Since the Origin seal.

We have exclusive satellites that monitor more than 80,000 supplier farms daily. Throughout the journey of the raw material, we are in control of the animal's well-being and comfort. All steps are dated, monitored, codified and, audited. This allows us complete confidence in the process and real-time traceability.

Quality control associated with cutting-edge technology is what ensures the integrity of collagen fibers in their most genuine, powerful, and pure state.

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